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Endocrine Abstracts

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ea0016p467 | Neuroendocrinology | ECE2008

Starting dose of 10 mg Octreotide-LAR appears ineffective for biochemical control in the majority of acromegalic patients: interim analysis from the OASIS trial

Petersenn Stephan , Tarasov Alexander , Gu Feng , Kim Sungwoon , Mercado Moises , Rogozinski Amelia , Bouterfa Hakim , David Kristin , Silva Antonio , Greenman Yona

Octreotide LAR (SMS-LAR) is available in 10, 20 and 30 mg dosing. The relation-ship between SMS-LAR starting dose and GH, IGF-I and symptoms was exam-ined. The Observational Acromegaly Study on Impact of Sandostatin LAR (OASIS) collects data on GH, IGF-I, symptoms, safety and tolerability in recently diagnosed acromegalic patients. Data are collected under normal practice conditions over 12 mos. Eight hundred and sixty patients from 138 centers in 23 countries are enrolled; 35...
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ea0014p550 | (1) | ECE2007

OASIS: observational study on the international clinical practice for the treatment of recently diagnosed acromegalic patients

Portocarrero Lesly , Akçay Güngör , Bouterfa Hakim , Carvalho Davide , Greenman Yona , Gu Feng , Guitelman Mirtha A , Kim Sungwoon , Kriesche Christine , Mercado Moises , Shen Chiung-Chi , Silva Antonio , Varela Cesar , Wallaschofski Henri , Webb Susan

Background: There is significant interest in how the use of different treatment regimens (e.g. surgery, medical therapy) impacts the clinical course of Acromegaly. This study has been designed to better understand clinical decision making in the context of various treatment options.Methods: OASIS is an international, observational study in recently diagnosed acromegalic patients. Ethical committee approval was obtained where applicable. Observations incl...
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Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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